Development and Investigation of Mesoporous Bioactive Glass/Zein Coatings Electrodeposited on Titanium Alloy for Biomedical Applications

Abstract The objective of the present work was development cathodic electrophoretic deposition (EPD) to obtain composite coatings mesoporous sol–gel glass (MSGG) particles embedded in a zein matrix on Ti-13Nb-13Zr substrates. To deposit robust and repeatable coatings, direct current EPD pulsed as well kinetics were investigated, including yield rate. stability suspension determined based zeta potential conductivity. Macroscopically homogeneous with thickness about 10 µ m various volume fractions MSGG subjected further examination. Coatings uniform, exhibiting open porosity showing excellent adhesion Both revealed an amorphous structure. coated substrates demonstrated greater resistance electrochemical corrosion Ringer's electrolyte comparison virgin (non-coated) substrate. showed high roughness moderate hydrophilicity. incubation concentrated 1.5 simulated body fluid (1.5SBF) formation carbonate hydroxyapatite. improved antibacterial properties against gram-negative E. coli gram-positive S. aureus bacteria compared pure coatings. Electrophoretic MSGG/zein should be investigated terms their osteoconductive behavior, confirm suitability for medical applications orthopedics.